The Role of Beta Sitosterol on MCF7, local AMJ13 cell lines and Staph. Aureus

Abstract

Abstract:
Phytosterols are biological active compounds which are naturally present in plant with chemostructure similar to the
eucayotic cell- derived cholesterol. They are highly available in lipid-rich plant foods such as nuts, seed, and olive oil.
- Sitosterol, as a single agent used in breast cancer cells MCF-7 cells and AMJ13 showed
treated with the following different concentrations: 0, 1, 10, 100, 1000, 10000, 100000 nm of -sitosterol .The
inhibition of viability showed much higher in MCF7 cell line than in AMJ13in - Sitosterol 10000,100000nm, the data
showed that - Sitosterol has controversial effect compared with previous studies . This study explained simply the
importance of - Sitosterol on MCF7 cell line compared with AMJ13 Furthermore, It clarified the antimicrobial
activity of - Sitosterol on Staphalococus aureus. This led that -Sitosterol may be used as a promising candidate
drug for anti-cancer in further medical researches