A comparative study of Prevalence and Antibiogram of Uropathogens in Patients with Urinary tract infection and Renal Stones in Al - Nasiriyah general Hospital

Abstract

Abstract
Aims: This study compared the prevalence, diversity, and antibiotic resistance profile of uropathogens in patients with UTI and patients with renal stones.
. Material and Method: mid stream urine spacemen were collected from 150 patients (75 with UTI and 75 with UTI and renal stone). Urine samples were collected from January 2024 to February 2025 from patients attending the Urology department in Al-Nasiriyah General Hospital. Mid-stream urine samples were inoculated directly on MacConkey and Blood agar and then incubated at 37°C for 24 hr Bacterial colonies were determined by standard culture and biochemical characteristics, and their susceptibility to different antibiotics was identified by the disk diffusion method.
Results: The mean age ± SD of the entire population 38.8±14.6, ranging from 13 to 68 years. Bacteriological investigation revealed that only 53 (35.3%) showed positive bacterial growth on culture media., statistical analysis showed no significant difference (P-value =0.494) in the overall bacterial recovery rates between UTI and stone former patients . . Six bacterial species were successfully identified, with E.coli being the most prevalent, 30.19%, followed by K pneumoniae, 22.6%, then P. aeruginosa and S. aureus, 16.9% and 15.09% respectively. E. Faecalis was the lowest prevalent, 5.66%.
In conclusion, no unique microbial signature is strongly associated with the formation of renal stones. and both urease-positive and negative can be isolated from UTI with renal stone